Chromatin Structure and Intellectual Disability Syndromes
نویسندگان
چکیده
منابع مشابه
SWI/SNF complex in disorder
Heterozygous germline mutations in components of switch/sucrose nonfermenting (SWI/SNF) chromatin remodeling complexes were recently identified in patients with non-syndromic intellectual disability, Coffin-Siris syndrome and Nicolaides-Baraitser syndrome. The common denominator of the phenotype of these patients is severe intellectual disability and speech delay. Somatic and germline mutations...
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